Vacation Home Rentals By Owner In Seneca, SC

$1295.33
/ Nightly

Private vacation home

Lake Break on Lake Keowee

Seneca, South Carolina, United States

4
Bed

4
Bath

11
Sleeps

$1124.48
/ Nightly

Private vacation home

Keowee Lakefront dock, canoe, kayaks, and more!

Seneca, South Carolina, United States

5
Bed

3
Bath

18
Sleeps

$1134.38
/ Nightly

Private vacation home

Casa Negra Clemson - 5 Bed Lake Home - 9 mi from Clemson - Pickleball court \n

Seneca, South Carolina, United States

5
Bed

4
Bath

17
Sleeps

$1172.64
/ Nightly

Private vacation home

Lake Keowee, Waterfront, Dock, Close to Clemson University

Seneca, South Carolina, United States

5
Bed

1
Bath

10
Sleeps

$1173.34
/ Nightly

Private vacation home

Spacious 5-Bed Lake Keowee Retreat – Only 15 Mins from Clemson!

Seneca, South Carolina, United States

5
Bed

4
Bath

12
Sleeps

$1190.90
/ Nightly

Private vacation home

Brand New 6BR/6BA Luxury Home, 20 min to Clemson. Flat lot/firepit/pool table!

Seneca, South Carolina, United States

6
Bed

6
Bath

14
Sleeps

$1212.17
/ Nightly

Private vacation home

Lake Point Haven with Dock

Seneca, South Carolina, United States

4
Bed

4
Bath

12
Sleeps

$1232.91
/ Nightly

Private vacation home

Large 5BR home on quiet cove. Pets welcome. Private dock. 3 fireplaces, firepit.

Seneca, South Carolina, United States

5
Bed

4
Bath

18
Sleeps

$1616.42
/ Nightly

Private vacation home

Summer's Way 185: Spacious 9 Bedroom Family Getaway in scenic Seneca, SC.

Seneca, South Carolina, United States

9
Bed

7
Bath

18
Sleeps

$1550.00
/ Nightly

Private vacation home

Sunset Ridge on Lake Keowee!

Seneca, South Carolina, United States

3
Bed

2
Bath

7
Sleeps