Vacation Home Rentals By Owner In Seneca, SC

Showing 191 Of 191 Vacation Rentals

$584.96

Cozy Lake Hartwell Retreat • Sleeps 12 • Deep Water Cove • 11 Miles from Clemson

Seneca, South Carolina, United States

Nestled in a peaceful deep-water cove in Seneca, this charming lake retreat offers the perfect combination of relaxation, comfort, and outdoor fun. With calm waters ideal for swimming, kayaking, paddleboarding, boating, and lounging by the lake, guests can fully enjoy everything lake life has to offer.brbrThe home features 3 beautifully appointed bedrooms on the main level, including 1 king bed and 2 queen beds. The spacious master bathroom includes a walk-in shower, jetted bathtub, hair dryer, and flat iron for added convenience. Each bedroom is equipped with a Smart TV and Roku access, making it easy to unwind after a day on the water.brbrDownstairs, the basement level offers a spacious family-style bedroom with garage access, featuring 1 king bed, 2 twin beds, a large TV, and a recliner — perfect for families or larger groups. Guests will also enjoy the cozy basement living area complete with a laundry space, additional refrigerator for food and beverages, 2 recliners, and 2 futons for extra sleeping arrangements. Entertainment options abound with a large TV, PS4 gaming system, and a wide selection of DVDs and PS4 games.brbrThere’s plenty of space to relax throughout the home, beginning with the inviting upstairs living room featuring a large sectional sofa, recliner, and swivel chair. Just steps away, the screened-in porch and expansive deck provide the perfect setting to enjoy your morning coffee, watch your favorite show outdoors, or simply take in the peaceful sounds of nature and stunning cove views.brbrExperience everything Seneca has to offer during your stay. Clemson University is just a short drive away, or enjoy a scenic boat ride to The Grill at Clemson Marina while spending the day fishing, cruising, or exploring the lake.brbrFor added security, an exterior camera is located above the garage and monitors the driveway area only.

Bed

Bath

Sleeps

Exceptional(4)

$345.03

/ Nightly

Private Vacation Home

NEW! Lakehouse Retreat near Clemson

Seneca, South Carolina, United States

This private home has 3 bedrooms and 2 full bathrooms, a fully equipped kitchen, two indoor living spaces, a large screened porch, and a desk with a gorgeous waterfront view if you need to get some work done on your getaway. There is a private dock for you to enjoy. The main floor bedrooms each have a queen bed. The kitchen has everything you need to cook and enjoy all your meals and the dining room seats 6. Outside you can fire up the propane grill or show off your smoking skills on the Pellet grill! Downstairs in the finished basement you’ll find a wet bar, desk area, extra living space, foosball, and a 3rd bedroom furnished with two sets of bunk beds. There is also a laundry room with washer/dryer should you need to run a load or two.

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Bath

Sleeps

Exceptional(2)

$66.74

/ Nightly

Private Vacation Home

bedroom available in my house in lovely Seneca. 5 miles from Clemson University

Seneca, South Carolina, United States

Inside, guests find a beautiful queen bed that promises restful nights. The bathroom features a hair dryer for added convenience. Climate control keeps the space comfortable with both heating and AC. Whether you’re relaxing indoors or planning your day, this marvelous house offers a brilliant blend of comfort and simplicity. I'm happy to assist with any questions while you stay at my house. Black out curtains for daytime sleeping. 100% use of kitchen. Washer and dryer across from your room. Extra storage if needed. Wifi and satellite TV available. You will have 100% access to the kitchen

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Sleeps

Exceptional(27)

$1338.34

/ Nightly

Private Vacation Home

New Lake House Overlooking Hartwell, Campus, and the Clemson Experimental Forest

Seneca, South Carolina, United States

Completed in 2022, 591 Tree Cat Trail is a five bedroom, five and a half bathroom home located in a secluded cove on Lake Hartwell next to Clemson University. Situated on a wooded hilltop, this home gives you a private mountain house feel with view of campus. Amenities such as a grocery store (Aldi), restaurants (Starbucks, Tipsy Taco, Five Guys, Lakeside Lodge’s Traditions, etc.), and shops (Marshalls, Five Below, Ulta, Mr. Knickerbockers, etc.) are a one-stoplight drive from the house. Across the cove from the house is the undeveloped Clemson Experimental Forest, providing peaceful views where it is common to hear turkeys gobble, spot nesting blue herons, and watch bald eagles catch fish. Once you leave the cove by boat, you will see Clemson’s campus, football stadium, and the big water of Lake Hartwell. The Clemson Marina is located outside of the cove as well and offers a restaurant, bar, and boat rental services. Fall is filled with the sights and sounds of football while spring has baseball, softball, and crew team races. Summer is all about enjoying the water and exploring beautiful Lake Hartwell. This home has a two story, max-size dock that can hold two guest boats plus two guest jet skis. The dock sits in deep water, so no matter the lake level, you are able to enjoy swimming, boating, and relaxing.br brMain Floor- master bedroom (king bed) with attached master bathroom; eat in kitchen with seating for 8 at the table and 5 at the island; screened in porch with fireplace and TV; lodge room with ample seating, fireplace and TV; powder ½ bathroom; huge back deck with grill, seating, dining table, and incredible views; main laundry room; drop zone areabr brWalkout Basement- Guest bedroom (king bed); bunk room (sleeps four); entertainment room with TV and games; patio; two full bathrooms; wet room with washer and dryer. br brSecond Floor- Two guest bedrooms (one queen bed located in each room). Both bedrooms have their own attached full bathroom; loft area with seating and TV.br brNearby lake features include restaurants accessible by boat such as the Clemson Marina, Sole’ on the Green, Your Pie, Wendy’s, and Pixie and Bill's. The Clemson Maria also has a boat ramp ($10 fee) and boat rentals.br br--Policies—br- No smoking.br br- No pets. Firm policy.br br- No events, parties, or large gatherings (This is not an event space)br br- Bath towels are provided. Lake towels are not provided and bath towels must not be used outside the house.br br- Must be at least 25 years old to rent.br br- Photo ID may be required at check in.br br- Additional fees and taxes may apply.br br--General—brThe kitchen comes fully equipped. Spices (salt pepper, etc.), bake ware, dishes, silverware, small appliances, etc. Two coffee makers are included (one Keurig and one drip coffee maker) along with coffee, filters, and k-cups. Paper towels (2 rolls), napkins (1 small pack), trash bags (4), dish soap, and dishwasher pods (4) are included. Any additional resources will need to be provided by the guest. Bed linens, pillows, and inside bath towels are included in the rental. Two washers and dryers (one set on main floor and one set in basement) are available for use. A limited amount of laundry pods and dryer sheets will be available for use, any additional will need to be provided by the guest. Bathrooms have toilet paper (2 rolls/each bathroom) and hand soap. Portable pack and play and high chair seat (sits in regular chair) are available for those with small children. Please contact host with any questions about the house or items provided.

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Bath

Sleeps

Exceptional(3)

$423.33

/ Nightly

Private Vacation Home

Pre-Revolutionary War Cabin on Lake Hartwell

Seneca, South Carolina, United States

Step Back in Time with Modern ComfortsRevolutionary War–Era Lakefront Cabin ️brWelcome to a rare piece of living history. Nestled on a private, wooded acre along the lake, this authentic Revolutionary War–era cabin offers a one-of-a-kind stay where timeless character meets modern comfort. ✨ Featured in several publications , this home has been lovingly preserved, allowing guests to experience the charm of the 18th century without sacrificing today’s conveniences.brWhere History & Comfort MeetFrom the moment you step inside, you’ll be surrounded by original woodwork, antique touches, and a warm, inviting atmosphere. Cozy up in the living room beside the gas fireplace , or spend evenings outdoors by the fireplace with firewood provided. The sunroom is a guest favorite—offering peaceful lake views , a mini bar , and a large TV for winding down after a day of exploring.brSleeping ArrangementsMain Level: King bedroom ️ with en-suite bathroom featuring a stand-up showerbrUpper Level: Bedroom with two Queen beds ️ ️ and a private en-suite bathroombrPerfect for couples, families, or a small group looking for comfort and privacy.brKitchen & DiningThe fully equipped kitchen ️ makes it easy to prepare everything from a quick breakfast to a relaxed evening meal after a day on the water.brOutdoor LivingStep outside and enjoy the spacious patio with ample seating—ideal for morning coffee, evening conversations, or simply soaking in nature. A gentle walk leads you to the lakefront, where your private dock is perfect for fishing or relaxing by the water (lake levels may vary).brLocation Highlights Boat Ramp: Just 0.5 miles awaybr ️ Downtown Seneca: 8 miles — dining, shopping, and local charmbr Clemson University: 10 miles — ideal for games, events, and campus visitsbrWhether you’re a history lover, a nature enthusiast, or simply craving a peaceful escape, this cabin offers a truly timeless retreat. Come slow down, unplug, and experience something unforgettable.brbrNO FIREWORKSbrNO PARTIES OR EVENTSbrMUST BE 25 TO RENTbr Mohawk Path, Seneca, United States 29678-6024

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Exceptional(79)

$370.43

/ Nightly

Private Vacation Home

Pirate's Retreat -Beautifully renovated lake home with Dock minutes from Clemson

Seneca, South Carolina, United States

Enjoy a relaxing stay on the water. Beautiful 3 bedroom, 2 bath home with everything from new appliances and furniture to small luxuries such as board games, DVDs, gas grill, 2 kayaks, 2 bikes, inflatable kayak, and outdoor games for your enjoyment. The property has a gorgeous view of the lake and mountains and is only a short 15 to 20 minute drive to Clemson University. Maybe you would like a mountain day trip to visit some local waterfalls or hit the trails, either skiing or off-roading, don't forget some shopping...endless possibilities. Walking distance from South Cove park where you can play tennis, pickleball, basketball, and use the boat ramp.

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Bath

Sleeps

Exceptional(49)

$497.2

/ Nightly

Private Vacation Home

Lake Keowee lakefront 4BR 3 bath home dock, screened porch, fire pit, tram.

Seneca, South Carolina, United States

This spacious and comfortable 3000sq ft. split level house is on the waterfront of beautiful Lake Keowee. Located off of Crooked Creek Rd in goodwater with 28' dock. Wide side of the dock can be used for guests boat. 3Kayaks available for guests. The house is not wheelchair accessible.brLarge fully equipped kitchen with island bar, 25 lb ice machine, and nook table. Separate dining room will seat up to 10. Living room upstairs overlooks the lake. br4 bedrooms and 3 full bathrooms. 2 bedrooms upstairs with outside balcony overlooking the lake with table and chairs. Master bedroom upstairs with private bathroom and TV. Large bedroom downstairs has 2 full size beds. Large family room downstairs, with tv, pull out sofa sleeper, older style exercise bike and air hockey table. Washer and dryer with laundry area. 1 full bathroom downstairs and 1 full bathroom upstairs. Outside deck overlooks the lake with gently sloping walk to the patio and firepit area and dock. Screened in porch overlooking lake with a covered area for grilling. Tram system runs from porch to fire pit area ( must agree to instructions before use). The house is not wheelchair accessible. Beautiful trees, shrubs and flowers in the yard to enjoy and keep you cool and relaxed. Nice area for walking around the neighborhood. Great neighborhood, quiet and friendly.brClose to Seneca for shopping. brThere are security cameras on the property and owners boats.

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Sleeps

Exceptional(11)

$219.09

/ Nightly

Private Vacation Home

3 Bedroom/2 Full Bath House in Seneca, SC. 4 miles from Clemson Campus!

Seneca, South Carolina, United States

Discover this charming 3-bedroom 2 full bathroom gem in Seneca, SC. This house boasts 2 queen beds and 1 twin over full bunk bed, perfect for a group getaway. Large front porch perfect for morning coffee or evening chats. With AC/heat, a washing machine, smart TV with hotspot capabilities, record player with vinyl collection, fully equipped kitchen, and included linens/supplies guests will have everything they need for a comfortable stay. The 2 bathrooms come equipped with a hair dryer and shower. This property is 4 miles from Clemson Campus, 1 Mile to Clemson Marina, and 2.5 miles from Seneca Creek boat ramp. Within walking/golf cart distance to Clemson Grill where you can have drinks, dinner, and overlook Lake Hartwell and the famous Death Valley Clemson Football Stadium. Golf cart/walking trail to lake front for fishing or relaxing. Enough space to comfortably park your boat, golf cart, or jet ski. Whether you are visiting someone at Clemson University, catching a Football game, or ready to do some fishing this is the perfect rental property. Kickback, relax, and enjoy everything Seneca and our house has to offer. (Host has boat, golf cart, and camper onsite not included in rental).

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Bath

Sleeps

Exceptional(12)

$459.5

/ Nightly

Private Vacation Home

Lake Keowee Home w/ Boat Dock in Seneca

Seneca, South Carolina, United States

Near Keowee Marina | Peaceful Location | Outdoor Smart TVbrbrExperience the tranquility of this 3-bedroom, 2-bath vacation rental situated along Lake Keowee in Seneca! This serene home features a furnished deck for sipping morning coffee and a full kitchen for preparing homemade meals to enjoy with loved ones. After days spent boating out on the lake or exploring High Falls County Park, head home to unwind and watch the sunset from the private dock.brbr-- THE PROPERTY --brbrSLEEPING ARRANGEMENTSbr- Bedroom 1: 1 king bedbr- Bedroom 2: 1 queen bedbr- Bedroom 3: 2 full bedsbr- Additional Sleeping: 1 portable cribbrbrKITCHENbr- All major appliances, including dishwasherbr- Dual drip/Keurig coffee maker, toasterbr- Cooking basics, trash bags/paper towels, dishware & flatwarebrbrINDOOR LIVINGbr- Smart TVbr- Laptop-friendly workspacebr- Ceiling fansbr- Dining tablebrbrOUTDOOR LIVINGbr- Furnished deck, fire tablebr- Boat dock/slipbr- HammockbrbrGENERALbr- Central heating & A/Cbr- Washer/dryer, laundry detergent, iron/boardbr- Linens/towels, hair dryerbr- Free WiFibr- Keyless entrybrbrFAQbr- Ring doorbell (facing out)br- Owner's boat may be on-site brbrACCESSIBILITYbr- Single-story home, 1 exterior step to enterbrbrPARKINGbr- Driveway (5 vehicles)br- Carport (2 vehicles)br- RV/trailer parking (side yard)brbr-- THE LOCATION --brbr- Peaceful waterfront location along Lake Keowee near hikingbr- 0.2 miles to Keowee Marina (boat rentals available)br- 7 miles to Clemson Universitybr- 9 miles to South Carolina Botanical Gardenbr- 18 miles to High Falls County Park & Stumphouse Tunnelbr- 50 miles to Greenville-Spartanburg International Airportbrbr-- REST EASY WITH US --brbrEvolve makes it easy to find and book properties you’ll never want to leave. You can relax knowing that our properties will always be ready for you and that we’ll answer the phone 24/7. Even better, if anything is off about your stay, we’ll make it right. You can count on our homes and our people to make you feel welcome — because we know what vacation means to you.brbr-- POLICIES --brbr- No smokingbr- No pets allowedbr- No events, parties, or large gatheringsbr- Additional fees and taxes may applybr- Photo ID may be required upon check-inbrbrADDITIONAL INFORMATIONbr- This single-story home requires 1 exterior step to enterbr- The owner's boat may be docked on-site, but there will still be 2 open spots for guest boatsbr- Your safety matters. This property features a Ring doorbell device with an exterior security camera facing the front outdoor entry. The camera does not look into any interior spaces. The camera actively records video when motion is detected by the device

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Sleeps

Exceptional(5)

$1134.38

/ Nightly

Private Vacation Home

Casa Negra Clemson - 5 Bed Lake Home - 9 mi from Clemson - Pickleball court n

Seneca, South Carolina, United States

Introducing our stunning new Lakehouse nestled on the serene shores of Lake Hartwell. This exquisite five-bedroom, four-bathroom retreat offers the perfect blend of modern luxury and natural beauty, making it the ideal haven for your lakeside getaway.brbrAs you step inside, you’ll be greeted by an open and inviting floor plan, designed to maximize the breathtaking lake views from every angle. The spacious living area features large windows that bathe the space in natural light and a cozy fireplace, perfect for relaxing with family and friends.brbrThe gourmet kitchen is a chef’s dream, boasting granite countertops, and an expansive island for meal preparation and casual dining. Adjacent to the kitchen, the dining area offers panoramic views of the lake, making every meal a memorable experience.brbrEach of the five bedrooms is a tranquil retreat, with comfortable furnishings and ample space for rest and relaxation. The master suite is a true sanctuary, complete with a private balcony overlooking the lake, a spa-like en-suite bathroom, and a walk-in closet.brbrStep outside to discover your own private paradise. The expansive deck is the perfect place to soak up the sun, entertain guests, or simply savor a morning coffee while taking in the serene lake views. Follow the path to your private dock, where you can swim, fish, or embark on leisurely boat rides across the pristine waters of Lake Hartwell.brbrLocated just 12 miles from Clemson University, this Lakehouse offers easy access to campus events and activities while providing a peaceful retreat away from the hustle and bustle. Whether you’re seeking a family vacation spot, a place to host gatherings with friends, or a serene escape from the everyday, our Lakehouse on Lake Hartwell promises an unforgettable experience. Book your stay today and immerse yourself in lakeside luxury and natural beauty. **must be 26 to book property and proof of age is required**

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Bath

Sleeps

Exceptional(155)

$421.33

/ Nightly

Private Vacation Home

Beautiful Lakefront Rental on Lake Keowee near Clemson. Pets welcome!

Seneca, South Carolina, United States

Monthly rate during off season (negotiable): $3000br brMore photos to come! We're currently renovating parts of the house for your convenience! The house will NOT be renovated during summer/fall season. brbrPET FRIENDLY!brbrEnjoy a relaxing vacation with your family at this magnificent waterfront home with breathtaking views of Lake Keowee.brbrThis spacious 3500+ square foot 4 bedroom 3 full bath home features an open floor plan with extra large windows overlooking beautiful Lake Keowee. Gentle sloping lot to the water. brbrThe main level has 1 bedroom (queen bed) and bathroom with walk-in shower, large laundry room, large sitting area (with Flat screen TV, DVD player, and radio), fully equipped kitchen, dining area, and covered deck area with a grill and fire pit. brbrThe upstairs has the master bedroom (queen bed) which has a loft window overlooking the lower sitting area. Also the bathroom on this floor has a large jetted tub for your enjoyment. This level also has its own sitting area overlooking beautiful Lake Keowee.br brThe lower level has 2 split bedrooms and 1 bathroom. One bedroom has two bunkbeds and the other has two queen beds. This level also has its own sitting area, with a computer and billiards table perfect for kids or teenagers. There is also a large dock that you will be able to dock your boats in (if you so desire). brbrLake Keowee is located in the foothills of the beautiful Blue Ridge mountains. Lake activities include swimming, boating, fishing, etc and there are breathtaking trails to hike around the area.brbrbrClemson University is only 25 minutes away and the historical town of Seneca is 10 minutes.br br•This is great rental for Clemson Football home games and big events like graduations. brbrThere is a 2 night minimum stay required. Cleaning fee of $150 is also applicable. brbr

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Most popular vacation rentals in Seneca

Exceptional(155)

$1295.33

/ Nightly

Private vacation home

Lake Break on Lake Keowee

Seneca, South Carolina, United States

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Exceptional(155)

$1124.48

/ Nightly

Private vacation home

Keowee Lakefront dock, canoe, kayaks, and more!

Seneca, South Carolina, United States

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Exceptional(155)

$1134.38

/ Nightly

Private vacation home

Casa Negra Clemson - 5 Bed Lake Home - 9 mi from Clemson - Pickleball court \n

Seneca, South Carolina, United States

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Exceptional(155)

$1172.64

/ Nightly

Private vacation home

Lake Keowee, Waterfront, Dock, Close to Clemson University

Seneca, South Carolina, United States

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Exceptional(155)

$1173.34

/ Nightly

Private vacation home

Spacious 5-Bed Lake Keowee Retreat – Only 15 Mins from Clemson!

Seneca, South Carolina, United States

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Exceptional(155)

$1190.90

/ Nightly

Private vacation home

Brand New 6BR/6BA Luxury Home, 20 min to Clemson. Flat lot/firepit/pool table!

Seneca, South Carolina, United States

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Exceptional(155)

$1212.17

/ Nightly

Private vacation home

Lake Point Haven with Dock

Seneca, South Carolina, United States

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Exceptional(155)

$1232.91

/ Nightly

Private vacation home

Large 5BR home on quiet cove. Pets welcome. Private dock. 3 fireplaces, firepit.

Seneca, South Carolina, United States

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Exceptional(155)

$1616.42

/ Nightly

Private vacation home

Summer's Way 185: Spacious 9 Bedroom Family Getaway in scenic Seneca, SC.

Seneca, South Carolina, United States

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Exceptional(155)

$1550.00

/ Nightly

Private vacation home

Sunset Ridge on Lake Keowee!

Seneca, South Carolina, United States

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Sleeps

Vacation Home Rentals By Owner In Seneca, SC

$584.96

$345.03

$66.74

$1338.34

$423.33

$370.43

$497.2

$219.09

$459.5

$1134.38

$421.33

Rent a place that suits your needs

Most popular vacation rentals in Seneca

$1295.33

$1124.48

$1134.38

$1172.64

$1173.34

$1190.90

$1212.17

$1232.91

$1616.42

$1550.00

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