Seneca: Vacation Rental By Owner

Beautiful 2 story family friendly home. Located on a large secluded lot on Lake Keowee without any neighbors on either side of the house. It is just a short 10... ...more

4 Bedroom, 3.5 Bathroom Lakefront Home, Bought in August 2019, New to VRBO! Entire interior and exterior completely renovated with brand new paint. All... ...more

Perfect waterfront vacation for the entire family. This 4 bedroom lake home sleeps 12 and offers all the essentials for a GREAT leisurely getaway. Our home... ...more

The White House, 5 bedroom, 3 1/2 bath, Lake Hartwell home across the lake from Clemson University. Perfect for visiting that special Clemson student, football... ...more

A perfect lake front get-away on Lake Keowee in Seneca South Carolina at the end of a dead end street with no traffic! Relax by the pool over looking the lake,... ...more

This beautiful home has 3 bedrooms, 2 bathrooms and sleeps 8 comfortably.  A dynamic open floor plan allows everyone to be spread out yet be together whether it... ...more

Amazing lakefront retreat ready to host your entire family! This 4 bedroom house is furnished with all the comforts of your home and ready to help you relax.... ...more

This new home sits on over an acre of land in a private lakefront setting at Lake Keowee in S.C. Large water views abound throughout the house. It has 4... ...more

This beautiful 2 story lake front home is set up for families to enjoy a relaxing time on the water or a quiet place to stay before catching a National Champion... ...more

At Wits Inn features a spacious, open floor plan with waterfront views from it's entire lakeside. Nestled in a mature wooded setting, highlights include a large... ...more

Offered for the First Time ever! Great Location! 3 large levels, 7 BR/7BA, 8,475 Luxurious square feet and sleeps up to 20! HUGE Master Suite with 100" Projection... ...more

Renting private walk out lower level of beautiful Lake front home. A dream lake house retreat: Walk-out level offers 2 bedrooms with attached 2 full baths, large... ...more

Lake Front House with large master on main with king sized bed, walk-in closet and a full bath. Main level has a 25' vaulted ceiling with exposed beams, two-story... ...more

Whether you're here for a relaxing lakefront getaway or to cheer on the Tigers, this impressive Seneca vacation rental townhouse is the perfect choice for you!... ...more

If you've been looking for a quality rental home on Lake Hartwell, the executive-style retreat called The Cove is exactly what you've been searching for. As you... ...more

Bask in the beautiful views of Lake Keowee when you stay at this 5-bedroom, 5-bathroom vacation rental house in Seneca. This newly constructed home boasts 4,800... ...more

Enjoy lake living at its finest at this newly remodeled 2-bed, 2-bath vacation rental nestled amongst the trees of Seneca. Boasting glistening water views from... ...more

Enjoy lake living at its best from this stunning vacation rental home right on Lake Keowee! With 3 bedrooms, 3 full bathrooms, and room for 10 guests, this rustic... ...more

If you’re looking to create life long memories, relax and unwind in a spacious and luxurious home, plus spend time on one of the most beautiful lakes in the... ...more

3 Level 2800 Sq. Ft. Lake House On Lake Hartwell 3.5 Miles From Clemson Stadium Two Living Areas Two Separate Full Kitchens Two Sets of Washers and Dryers Large... ...more