Serenity South -- Gardens, River-Views, and Refreshing Space

Cape Girardeau, Missouri
$191 avg/night
Minimum Stay 1 Nights
Bed 3

Bed

Bath 1

Bath

Home Private Vacation Home

Property Type

Sleep 5

Max Sleeps

Night 1 nights

Min Stay

Beautifully renovated duplex with large shared yard in Cape Girardeau Historic District. Cozy living room, large dining room, fully stocked kitchen, 3 second-story bedrooms with balcony at the end of the hall, and 1 1/2 bathes. Perfect for getting away for rejuvenation or exploring downtown. Within walking distance to local downtown restaurants, antique shops, and boutiques. Two blocks from the Mississippi River and many other attractions.

  • Feature Features
  • Map Map
  • School District Availability
  • Review Review

Feature Features

  • PETS

    No Pets Allowed
  • SAFETY

    Carbon Monoxide Detector Installed (host Has Indicated There Is A Carbon Monoxide Detector On The Property) Deadbolt Lock Smoke Detector Installed (host Has Indicated There Is A Smoke Detector On The Property)
  • BEDROOM

    3 Bedrooms Bed Sheets Provided
  • GENERAL

    Unit Size: 1600 Sq Ft (149 Sq M)
  • KITCHEN

    Coffee/tea Maker Dishwasher Microwave Oven Paper Towels Refrigerator Spices Stovetop Toaster
  • LAUNDRY

    Near Laundromat
  • PARKING

    Car Not Required Onsite Parking
  • INTERNET

    WiFi Available
  • OUTDOORS

    Balcony Garden Outdoor Furniture
  • BATHROOMS

    1.5 Bathrooms Bathtub Or Shower Hair Dryer Shampoo Soap Toilet Paper Towels Provided
  • LANGS SPOKEN

    English
  • THINGS TO DO

    Cycling Nearby Fishing Nearby Fitness Facilities Nearby Golf Nearby Horse Riding Nearby Power Boating Nearby Swimming Nearby Water Park Nearby Wildlife And Game Walks Nearby Winery Tours Nearby
  • ENTERTAINMENT

    Books DVD Player Games TV
  • LIVING SPACES

    Dining Room Fireplace
  • CLIMATE CONTROL

    Air Conditioning Heating
  • FAMILY FRIENDLY

    Children's Games Playground
  • LOCATION HIGHLIGHTS

    Near A Health Or Beauty Spa Near A Hospital Near Outlet Shopping On The River
  • SERVICES AND CONVENIENCES

    Iron/ironing Board
  • SUITABILITY/ACCESSIBILITY

    Smoke-free Property

CheckIn Check-in : 04:00 PM CheckOut Check-out : 11:00 AM
No Wheelchair No smoking No pets Children allowed
Occupancy Max occupancy : 5

Map Map

School District Availability

Review Review

  • John

    Submitted Dec 10, 2023

    Stayed Dec 9, 2023

    Great place.

  • Submitted May 3, 2021

    Stayed Apr 30, 2021

    It had a historical quaint duplex. Scones were delightful and owners were SO responsive to questions. So close to riverfront park and downtown.

  • Sandy S.

    Submitted Apr 17, 2026

    Stayed Apr 2, 2026

    although short, stay was enjoyable and comfortable..Really nice neighbors and neighborhood..ease to walk to park for the grand kids to play and easy access to restaurants near by all within walking distance.

  • John M.

    Submitted Mar 22, 2026

    Stayed Mar 20, 2026

    This is a beautiful, well-maintained historic home in a neat part of town -- walking distance to lots of attractions. The hospitality was off the charts. Every detail was thought out. Bed was comfortable, AC worked great, and wonderful spaces (dining room, living room, porch) to hang out in!

  • Marcie R.

    Submitted Feb 15, 2026

    Stayed Feb 14, 2026

    Nice location to river front and downtown. Very lovely place.

  • Vicki R.

    Submitted Jan 12, 2026

    Stayed Dec 24, 2025

    It's a great location, great space, great price. And, the muffins are the best!

  • Tamy R.

    Submitted Dec 15, 2025

    Stayed Dec 12, 2025

    Host was fantastic. House is just like the pictures.

  • Alison C.

    Submitted Nov 25, 2025

    Stayed Nov 20, 2025

    Wonderful location! WonderfulStay

  • Michael W.

    Submitted Nov 10, 2025

    Stayed Oct 31, 2025

    All was good except for the strange fact of 3 rentals at the same place and the older couple in the backyard was a little off putting.

  • Isaac S.

    Submitted Oct 22, 2025

    Stayed Oct 17, 2025

    Home was very tidy, kitchen was spacious, and bedrooms comfortable.

  • Michael R.

    Submitted Oct 14, 2025

    Stayed Oct 10, 2025

    Nice property near downtown in the river. This was the perfect location for our 50th high school reunion.

  • Shelley L.

    Submitted Sep 30, 2025

    Stayed Sep 29, 2025

    Good stay.

  • Sandy M.

    Submitted Sep 28, 2025

    Stayed Sep 25, 2025

    We were visiting our daughter who attends SEMO, so the location was perfect.

  • Deborah K.

    Submitted Sep 21, 2025

    Stayed Sep 20, 2025

    Charming house within walking distance to downtown restaurants and bars. Host is wonderful! Great communication.

  • Donna D.

    Submitted Aug 11, 2025

    Stayed Aug 10, 2025

    Moving our daughter in to the dorm at SEMO for yr 2. Been coming to this location since our trip here during her senior year of HS when she visited SEMO to audition for the musical theatre program. It is a great place to stay when you have more than 2 people.

  • Tracy H.

    Submitted Aug 1, 2025

    Stayed Jul 30, 2025

    Such a great place and location

  • Jodie F.

    Submitted Jul 26, 2025

    Stayed Jul 17, 2025

    Enjoyed everything! Great location!

  • Nichole C.

    Submitted Jul 25, 2025

    Stayed Jul 22, 2025

    Serenity south was welcoming comfortable and very clean. Impeccably maintained historic home. Comfortable beds, great water pressure and shower head, easy to maintain consistent temperature. Good vibes throughout. Not haunted. Beautiful outdoor space but it was too hot to use it much while we were there. Recommend stopping by the olive oil store William and Water across the street.

  • Bryan P.

    Submitted Jul 1, 2025

    Stayed Jun 19, 2025

    Great Location short walking distance to the Downtown Area with lots do do, Restaurants, Water Park, Shopping. This is the 2nd time I have stayed and it is a true delight. Very spacious and comfortable. Easy to communicate with the Owner/Manager. I will be staying there again in the future. I recommend it with 5 Stars!

  • Vicki R.

    Submitted Jun 9, 2025

    Stayed Jun 7, 2025

    Beautiful house. Great stay. Would definitely stay again!

  • Linden S.

    Submitted Jun 1, 2025

    Stayed May 30, 2025

    Three generations found rest,beauty,& joy at Serenity South. Thoughtful touches,beautiful gardens and Cape charm made this more than a stay-it became a treasured memory. We were so appreciative of the details, the fresh flowers, homemade cookies, the coffeemaker upstairs and the books and games. The beds were all comfortable. We enjoyed this historical home and our stay.

  • STEPHANIE L.

    Submitted May 19, 2025

    Stayed May 17, 2025

    Its was different, but over all it was on point.I will rebook this summer

  • Sam E.

    Submitted Apr 19, 2025

    Stayed Apr 12, 2025

    My son and two brothers stayed a night in this lovely home. I travel to Cape frequently to visit my son and will definitely stay here again.

  • Michelle K.

    Submitted Mar 28, 2025

    Stayed Feb 27, 2025

    When looking for a VRBO for our daughter's college visit, we knew the perfect place to stay! This is our second stay at Serenity South and it was just as incredible as the first visit. Clean, inviting and cozy. Thanks Jo for another beautiful stay.

  • Penny F.

    Submitted Mar 28, 2025

    Stayed Mar 14, 2025

    The property was exactly as listed with so many little touches that made it special. Communication was great and we were close to downtown shops and the casino. We will definitely stay again when we are in the area.

  • Rhonda S.

    Submitted Feb 23, 2025

    Stayed Feb 21, 2025

    We had a wonderful time at Serenity South! The house is quiet and very clean, in walking distance of fantastic shops and fun places to eat. We look forward to returning next year!

  • shirley g.

    Submitted Feb 18, 2025

    Stayed Feb 14, 2025

    Here for a volleyball tournament. Had 3 short days to enjoy this beautiful home. Just not long enough. Has everything u need and more. Jo is a lovely host. So quiet and peaceful.. most of all in a safe area. I plan to go back by summers end just so I can enjoy the home and walk to coffee shop and tour the old part of town. Just wonderful!

  • Jennifer K.

    Submitted Dec 30, 2024

    Stayed Dec 26, 2024

    This is an older home (1920’s?) with so much charm. It’s exceptionally well cared for - the floors are clean and in excellent condition, the walls are clean, paint job is beautiful, etc. The air is clean (no smell of mold) bathroom fans work, etc! In short, one of the best maintained rentals we’ve stayed in. The beds are comfy. Oh - and the landscaping is also beautiful! It is winter - would love to see the gardens in the spring. Jo was easy to contact, check in was easy. The trains do run 1 or 2 times per night and are close and on Friday night there were some people having fun running their loud cars through town but otherwise it is quiet and peaceful. The walk to town is only a few blocks. We would definitely stay here again!

  • Michelle A B.

    Submitted Dec 16, 2024

    Stayed Dec 14, 2024

    This was the second year in a row that we have stayed here. This is a beautiful home to stay in. I love the charm and detail of the house. We stay here after a Christmas party and walk downtown so it’s definitely located in a convenient spot. I will be booking again for next year Great communication with Jo and if there’s any questions I need, Jo is very quick to respond. Thank you for making our stay good!

  • Steve B.

    Submitted Nov 4, 2024

    Stayed Oct 28, 2024

    Very nice property. Highly recommend.

  • joe R.

    Submitted Oct 21, 2024

    Stayed Oct 19, 2024

    Beautiful very clean house with a lot of character

  • Debbie K.

    Submitted Sep 29, 2024

    Stayed Sep 28, 2024

    We stayed at Serenity South instead of a hotel for family weekend. We were able to have our daughter and her friends over for dinner which we could never do in a hotel! There are great views from upstairs.

  • Scott R.

    Submitted Sep 11, 2024

    Stayed Sep 6, 2024

    Nice property, real close to downtown and the river. Very relaxing

  • Tracy H.

    Submitted Sep 2, 2024

    Stayed Aug 30, 2024

    We were a last minute stay and Jo quickly accommodated. She had the air conditioning on for us and fresh flowers. So wonderful

  • Mom 2.

    Submitted Aug 18, 2024

    Stayed Aug 13, 2024

    I have stayed at Serenity South three times in the last 5 months. It is perfectly located near downtown restaurants and the Old St. Vincent's church, and it is literally a 2 minute drive to SEMO's River Campus. We will be returning to Cape next month, but sadly, this property was already booked. It will always be my first choice, though.

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Total

Includes taxes and fees
$242+
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